检测结核抗体诊断结核病价值的研究  

Clinical Significance of Serum Anti-mycobacterium Tuberculosis Antibody in Diagnosis of Tuberculosis

作　　者：刘三都[1] 唐菊菊 鲍崇忠[1] 杨庆坤 王吉超[1] 舒德云 

机构地区：[1]黔南民族医学高等专科学校附院传染科,都匀558000

出　　处：《黔南民族医专学报》1999年第4期198-200,共3页Journal of Qiannan Medical College for Nationalities

摘　　要：目的:研究结核抗体在活动性结核病诊断和监测病情变化的临床意义。方法:观察血清结核抗体在各类结核患者的敏感性和特异性,与脑脊液,胸腹水结核抗体的关系,与痰涂片及PPD皮试的一致性,以及与疾病转归的关系。结果:血清结核抗体诊断结核病的敏感性为82.6％,特异性为90.2％,脑脊液、胸腹水结核抗体阳性OD值>血清结核抗体阳性OD值对诊断结核性脑膜炎、结核性胸膜炎及腹膜炎具有定性定位价值,与痰涂片阳性和PPD皮试阳性的一致率分别为89.8％和75.2％,结核抗体水平与病情变化有一定相关性。结论:结核抗体可用来诊断活动性结核病及评估结核病的转归。Objective: To evaluate the clinical signicance of serum antimyclbacterium tuberculosis antibody in diagnosis of tuberculosis. Methods: Sensitivity and specificty of the antibldy in diagnosis of tuberculosis were detected. The relationship between serum antibody and the antibody in cerebrospinal fluid, hydrothorax and hydroabdomen was observes. Results of the antibldy detection, sputum smear and PPD examination were compared, and the relationship between the level of the antibody and the situation of the disease was also lbserved. Results: The sensitivity lf the antibody in diagnosis of tuberculosis was found to be 82.6 %, while the specificity 90.2 %. The result of to observe the level of the antibody in cerebrospinal fluid, hydrothorax and hydroabdomen was mach higher than that in serum have to diagnosing significance for situation. The consistant rates of the antibody with with sputum smcar and PPD test were 89.8% and 75.2% respectively. The level of the antibody was related with the situation of the disease. Conclusion: Detection of the antibody is helpful for diagnosing tuberculosis and can be used to eveluate the prognosis of the disease.

关 键 词：结核抗体 诊断 结核病 

分 类 号：R52[医药卫生—内科学]