三(2—苯并咪唑亚甲基)胺的铜(Ⅱ)和锌(Ⅱ)配合物的合成及结构分析  

Synthesis and Analysis of the structure of the Copper (I) and zinc (I) complexes donated by tri (2-benzimi-dazylmethyl )amine

作　　者：郭洪声[1] 王敏[2] 邓桂茹[1] 龚海英[1] 

机构地区：[1]武警医学院化学教研室,天津300162 [2]天津市津华中学,天津300162

出　　处：《武警后勤学院学报（医学版）》1998年第1期12-14,共3页Journal of Logistics University of PAP（Medical Sciences）

摘　　要：目的:为人工模拟合成超氧化物歧化酶（Super Oxide Dismutase）首先合成一系列以三（2—苯并咪唑亚甲基）胺（简称NTB）为配体的过渡金属离子单核配合物,以研究其结构。方法:以Cu（NO₃）₂·6H₂O和Zn（NO₃）₂·6H₂O为原料,分别与配体NTB于甲醇中共热,粗产物重结晶后。溶于二甲亚砜中,由Cu（Ⅱ）得到蓝色长方形晶体,由Zn（n）得到无色长方形晶体。对所得产物分别进行红外光谱分析和x—射线晶体结构测定。结果:x—射线晶体结构分析表明,由Cu（Ⅱ）所得晶体属于三斜晶系,其空间群为P_-1（No.2）,晶胞参数为a=9.865（?）b=12.666（?）c=14.889（?）·α=94.93⁰β=100.8⁰γ=107.31⁰,最终的偏离因子R=0.072;由Zn（Ⅱ）听得的晶体属于四方晶系,空间群为I₄₂（No.122）,晶胞参数为a=22.349（?）b=22.349（?）c=22.255（?）。最终偏离因子R=0.061。结论:以NTB为配体,合成了其Cu（Ⅱ）和Zn（Ⅱ）配合物,并测定了其结构,并与人体细胞中的SOD结构做了比较,为人工模拟合成SOD提供了理论和实验基础。Objectives: Synthesize a series of transition metalcomplexes donated by tri ( 2 - benzimidazylmethyl ) a mine toimitate superoxide dismutase (SOD), and analyse its crystal structure. Methods : Cu (NO3 )2 · 6H2O and Zn (NO )2 · 6H2O were dissolved and heated tn methol with NTB respectively .the production was dissolved in DMSO and the blue and colorless single crystal were sbtained. The IR Spectra.crystal structure were determined. Results:Thecrys-tallographic data of Copper ( Ⅱ )complexe as follows :Triclinic space group P-1 (No. 2)a-9. 865 A b = 12. 666 A c= 14. 889 A , α= 94. 93 , β= 100. 81 γ= 107. 31. The crystallographic of Zinc ( Ⅱ )complexe as follows; Tetragonal. Space groupI4 (No. 122)a=22. 349,A b = 22. 349 A c = 22. 255 A. Conclusions:In this paper .the synthesis and structure of the mononuclear complexes of Cu( Ⅱ )and Zn( Ⅱ )and compare theirstructures with that of SOD in human body's cell.

关 键 词：三(2—苯并咪唑亚甲基)胺 铜(Ⅱ)配合物 锌(Ⅱ)配合物红外光谱分析 结构测定 

分 类 号：O641.4[理学—物理化学]