The Diagnosis of Diffuse Goitre by Ultrasound Imaging in Children  

作　　者：方俊敏 朱明华 黎春蕾 张青萍 王慕逖 

出　　处：《Journal of Huazhong University of Science and Technology(Medical Sciences)》1998年第1期61-64,共4页华中科技大学学报（医学英德文版）

摘　　要：In order to find an easy and accurate procedure for diagnosis of diffuse goitre in children, we examined 50 patients with diffuse goitre using fine needle aspiration biopsy cytology, thyroid antibody detection, thyroid hormone analysis and ultrasound imaging. In the meantime, 109 healthy children (control) were examined by ultrasound imaging. The results showed that thyroid imaging in health children was a smooth echo pattern with stronger homogenous echogram than surrounding muscle tissues. The patients with diffuse goitre showed an normally enlarged thyroid volume. In 22 (84. 6 %) of 26 children With chronic lymphocytic thyroiditis, a varied patch hypoechogenicity was found, of whom 18 (81. 8 % ) had positive results of antibody testing. On the contrary, echo-pattern was normal in 17 (70. 8 %) of 24 patients with diffuse thyroid proliferation and only the remainder (7/24, 29. 1% ) had abnormal echo-pattern as well as elevated auto-antibody titers, of whom 2 were confirmed as chronic lymphocytic thyroiditis by a repeat fine needle aspiration biopsy 1 year later. By using combined ultrasound imaging and antibody determination, 92 % of the cases with chronic lymphocytic thyroiditis could be diagnosed. Our study suggests that ultrasonic imaging is an easy, non-invasive, reproducible and effective procedure in the differen,tial diagnosis of chronic lymphocytic thyroiditis in children.In order to find an easy and accurate procedure for diagnosis of diffuse goitre in children, we examined 50 patients with diffuse goitre using fine needle aspiration biopsy cytology, thyroid antibody detection, thyroid hormone analysis and ultrasound imaging. In the meantime, 109 healthy children (control) were examined by ultrasound imaging. The results showed that thyroid imaging in health children was a smooth echo pattern with stronger homogenous echogram than surrounding muscle tissues. The patients with diffuse goitre showed an normally enlarged thyroid volume. In 22 (84. 6 %) of 26 children With chronic lymphocytic thyroiditis, a varied patch hypoechogenicity was found, of whom 18 (81. 8 % ) had positive results of antibody testing. On the contrary, echo-pattern was normal in 17 (70. 8 %) of 24 patients with diffuse thyroid proliferation and only the remainder (7/24, 29. 1% ) had abnormal echo-pattern as well as elevated auto-antibody titers, of whom 2 were confirmed as chronic lymphocytic thyroiditis by a repeat fine needle aspiration biopsy 1 year later. By using combined ultrasound imaging and antibody determination, 92 % of the cases with chronic lymphocytic thyroiditis could be diagnosed. Our study suggests that ultrasonic imaging is an easy, non-invasive, reproducible and effective procedure in the differen,tial diagnosis of chronic lymphocytic thyroiditis in children.

关 键 词：diffuse goitre chronic lymphocytic thyroiditis ultrasound imaging AUTO-ANTIBODY 

分 类 号：R445.1[医药卫生—影像医学与核医学]