Fast electron transfer repair of oxidizing OH adduct of dGMP by chlorogenic acid  

作　　者：马建华 钱素平 林维真 姚思德 

出　　处：《Science China Chemistry》1998年第5期556-560,共5页中国科学（化学英文版）

基　　金：ProjectsupportedbytheNationalNaturalScienceFoundationofChina (GrantNo .39130 0 5 0 )

摘　　要：Pulse radiolysis of chlorogenic acid (CGA) as well as CGA and 2′\|deoxyguanosine\|5′\|monophosphate (dGMP) has been carried out in aqueous solution using pulse radiolytic technique. From detailed kinetic analyses, the kinetic parameters have been obtained. Accordingly, the reaction mechanisms are suggested. Previous studies have indicated that CGA can either scavenge OH radical or repair oxidizing OH radical adduct of dGMP effectively.Pulse radiolysis of chlorogenic acid (CGA) as well as CGA and 2′-deoxyguanosine-5′-monophosphate (dGMP) has been carried out in aqueous solution using pulse radiolytic technique. From detailed kinetic analyses, the kinetic parameters have been obtained. Accordingly, the reaction mechanisms are suggested. Previous studies have indicated that CGA can either scavenge OH radical or repair oxidizing OH radical adduct of dGMP effectively.

关 键 词：pulse RADIOLYSIS chlorogenic acid 2′\|deoxyguanosine\|5′\|monophosphate. 

分 类 号：Q503[生物学—生物化学]