不同溶解液青霉素肌注所致臀肌挛缩的实验研究  

Experimental study of gluteus muscle contracture induced by different penicillin solvent intramuscular injection

作　　者：吴越[1] 张强[1] 徐庭梅 张红[1] 

机构地区：[1]山东省泰安市解放军第88医院全军骨科中心,271000

出　　处：《实用骨科杂志》1997年第4期222-224,共3页Journal of Practical Orthopaedics

摘　　要：注射性臂肌挛缩症的发病机理还不清楚,本试验应用不同的溶解液溶解青霉素后肌注30只幼兔的臀部。A组,生理盐水+青霉素组,6只;B组:5％葡萄糖盐水注射液+青霉素组,6只;D组:注射用水+青霉素组,6只;E组:仅注射不注药6只。结果表明A、B、CD四组均可引起臀肌挛缩症,其中A组:1只;B组:3只;C组;4只;D组;2只。作者认为溶解液的渗透压和注射后血肿形成是臀肌挛缩的主要原因,根据实验结果建议生理盐水是最佳溶剂,10％葡萄糖注射液和5％葡萄糖盐水注射液不能作为肌注青霉素的溶解液。The pathogenesis of gluteus muscle contracture is not very clear, in this study different penicillin solvent were injected into the bilateral buttocks of 30 growing rabbits to observe the pathogenesis. Group A NS + penicillin group, B 5% GNS + penicillin,group C 10%GS + penicillin group D DW + penicillin group E as the control group. The results showed that four group all can induce gluteus muscle contractrue group A:1, group B:3, group C:4, group D:2-The authors thought that solvent osmopres-sure and haematoma formed after the injection are the important factor of the contracture. According to the results it is suggested that NS is the best solvent and 10% GS, 5%GNS be not used as a solvent of eni-cillin for intramuscullar injietion.

关 键 词：臀肌挛缩症 肌注 不同的溶解 发病原因 

分 类 号：R685[医药卫生—骨科学]