硫酸镍对红细胞毒性研究  

Influence of nickel sulfate on RBC of mice.

作　　者：谈兰英 孙应彪[1] 朱玉真[1] 

机构地区：[1]兰州医学院卫生学毒理学教研室

出　　处：《甘肃医药》1997年第5期251-252,5,共3页Gansu Medical Journal

摘　　要：健康小鼠腹腔注射硫酸镍10.0,5.0,2.5mg/kg,导致外周血中红细胞增高,血红蛋白不变或降低,红细胞中点彩红细胞和碱粒红细胞占有比值明显增高,网织红细胞含量升高、提示镍对外周血红细胞有毒性损害。The health mice were injected (in-traperitoneal) nickel sulfate (NiSO4) 10.0, 5. 0,2. 5 mg/kg. The results reveal that RBC count in peripheral blood increased, hemoglobin(Hb) unchanged or diminished,ratio of stripping and basophilic erythrocyte obviously increased, reticulated corpuscles increased, and propose that nickel sulfate has toxic damage on RBC of mice.

关 键 词：硫酸镍(NiSO₄) 点彩红细胞 碱粒红细胞 网织红细胞 

分 类 号：R114[医药卫生—卫生毒理学]