Quantitativ　estructure－activity　relationships　for　studying　alkyl（1－phenylsulfonyl）　cycloalkane－carboxylates  

作　　者：He Yibing Wang Liansheng (Department of Environmental Science and Engineering, Nanjing University, Nanjing 210093, China) 

出　　处：《Journal of Environmental Sciences》1996年第2期157-166,共10页环境科学学报（英文版）

摘　　要：Octanol/water partition coefficients,adsorption coefficients for soils and sediments and acute toxicities to Daphnia magna of 28 alkyl (1-phenylsulfonyl) cycloalkane-carboxylates were measured. These properties were correlated by linear solvation energy relationship (LSER) and chromatographic retention data determined by reverse-phase high performance liquid chromatography (RP-HPLC). The accuracy and range of applicability of these two quantitative structure-activity relationship (QSAR) methods were compared in this paper.Octanol/water partition coefficients,adsorption coefficients for soils and sediments and acute toxicities to Daphnia magna of 28 alkyl (1-phenylsulfonyl) cycloalkane-carboxylates were measured. These properties were correlated by linear solvation energy relationship (LSER) and chromatographic retention data determined by reverse-phase high performance liquid chromatography (RP-HPLC). The accuracy and range of applicability of these two quantitative structure-activity relationship (QSAR) methods were compared in this paper.

关 键 词：alkyl (1-phenylsulfonyl) cycloalkane-carboxylates LSER R-PHPLC. 

分 类 号：X51[环境科学与工程—环境工程]