HPLC监测的人参皂甙在温和酸性条件下的降解变化  

Degradation of Ginsenosides Under Mild Acidic Conditions Monitored by High Performance Liquid Chroma tography

作　　者：冯仲扬[1] 张燮[2] 

机构地区：[1]大连大学医学检验系,大连116622 [2]吉林大学化学系,长春130021

出　　处：《大连大学学报》1996年第4期354-359,共6页Journal of Dalian University

摘　　要：对人参皂甙20(s)-原人参二醇组中的两种主要单体皂甙Rd与Rb_1在近似胃液条件下的酸水解情况以HPLC法进行了分析检测,结果表明:人参皂甙Rd降解产生次级甙20(s)一Rg_3和F_2;Rb_1降解产生次级甙20(s)-Rg_3、F_2和Rd.综合这些研究,文中对该条件下皂甙甙键的裂解顺序、次级甙的衍生规律以及水解相关因素的影响亦做了初步探讨与归纳。Hydrolysis of two kind of the main ginsenosides of the 20 (s) - protopanaxadioi groop under a condition similar t artifical gastric fluid has been researched. Degradation processes have been monitored by HPLC method. The results of this study prove that under the hydrolysis condition, ginsenoside -Rd decomposed' to yield prosapogenins: 20 (s) - Rg3 and F2; ginsenoside -Rb1 yieled prosapogenins:Rd, 20(s) -Rg3 and F2; According to this work, the present paper has investigated further the cracking sequences of the saponin bonds and the derivative laws of the prosapogenins under the condition.

关 键 词：人参 人参皂甙 HPLC 

分 类 号：O657.7[理学—分析化学]