Induction of apoptosis in HL-60 cells by harringtonine  

作　　者：方敏 张鸿卿 薛绍白 庞大本 池旭生 

机构地区：[1]Department of Biology, Beijing Normal University, Beijing 100875, China [2]Basal Institute of Chinese Academy of Traditional Medicine, Beijing 100700, China

出　　处：《Chinese Science Bulletin》1995年第11期939-944,共6页

基　　金：Project supported by the National Natural Science Foundation of China and the Foundation for Doctors Cultivation from States Education Committee of China.

摘　　要：Recently, many reports showed that most of cytotoxic anticancer drugs in current usesuch as DNA topoisomerase Ⅰinhibitor camptothecin (CAM), or DNA topoisomerase Ⅱinhibitor teniposide (TEN) could induee apoptosis in susceptible cells. Apoptosis (Apo),which is different from necrosis (Nec), is a specific mode of cell death recognized by thecharacteristic pattern of condensation of chromatin, integrity of plasma membrane and

关 键 词：APOPTOSIS HL-60 CELL harringtonine. 

分 类 号：O629[理学—有机化学]