Analysis of aromatic sulfur-containing compounds based on free-Wilson method  

作　　者：洪晖 韩朔睽 王连生 赵元慧 邹公伟 张正 

机构地区：[1]Department of Environmental Science and Engineering, Nanjing University, Nanjing 210008, China [2]Department of Chemistry, Nanjing University, Nanjing 210008, China

出　　处：《Chinese Science Bulletin》1995年第19期1621-1624,共4页

基　　金：Project supported by the National Natural Science Foundation of China.

摘　　要：In the study of quantitative structure-activity relationships (QSARs), Hansch’s linear free-energy relationships (LFERs) are the most commonly used. However, LFERs have many limitations. Free-Wilson method has its specialties in the study of QSARs. It is es pecially suitable for the compounds of the same parent structure and with this method, the physicochemical parameters of the compounds are not necessarily calculated. The method can give the contribution of each substitute on each position. Though free-Wilson

关 键 词：STRUCTURE-ACTIVITY free-Wilson method. 

分 类 号：O621[理学—有机化学]