铝的毒性研究（Ⅲ）─—铝暴露的高危人群探讨  

STUDY ON TOXICITY OF ALUMINUM:(Ⅲ)HIGH RISK POPULATION EXPOSED TO ALUMINIUM

作　　者：徐格晟[1] 孙增荣[1] 张振文[1] 任大林[1] 黄国伟[1] 张万起[1] 

机构地区：[1]天津医学院

出　　处：《中国食品卫生杂志》1994年第1期7-10,41+66,共6页Chinese Journal of Food Hygiene

摘　　要：用病例、对照的流行病学调查方法，对１２２例慢性肾功能不全患者及２７例老年性痴呆患者进行铝与此两种疾病关系的研究。结果显示慢性肾功能不全及老年性痴呆患者的体内铝负荷较高，反映铝是慢性肾功能不全患者早期大脑功能减退的危险因素之一，也反映血铝增高与老年性痴呆症关系密切。初步认为慢性肾功能不全及老年性痴呆患者是环境铝暴露的高危人群，应注意限制他们的高铝食品摄入。Abstractthe case/control study method was used in this Epidemiological survery.This study included 122 cases from chronicrenal insufficiency and 27 cases suffer from senile dementia.The results showed that high levels of Aluminum was demonstreted in the blood δhair of those patients.It was concluded that Aluminum is one of risk factors of early stage of brian hypo-function and high content of Aluminum in blood is closely related to senile dementia.We preliminary consider that the high risk population exposed to Aluminum in environment are these suffering from chronic renal insufficiency and senile dementia.

关 键 词：高危人群 毒性研究 老年性痴呆症 功能不全 修订韦氏成人智力量表 血铝 慢性肾 危险因素 多元逐步回归分析 透析性脑病 

分 类 号：R114[医药卫生—卫生毒理学]