新型血小板聚集功能缺陷症——发病情况和诊断指标的商榷  

A New Variant of Platelet Aggregation Defect—Discussion on Incidence and Diagnostic Criteria

作　　者：沈迪[1] 王爱莲[1] 凌柱三[2] 夏锦如 徐敏[2] 李武福 岳育新 刘泽霖[4] 许建邦[4] 

机构地区：[1]同济医科大学附属协和医院 [2]湖南医科大学附属第二医院 [3]佳木斯市医学科学研究所 [4]广州医学院附属第二医院

出　　处：《临床血液学杂志》1990年第2期49-51,共3页Journal of Clinical Hematology

基　　金：国家自然科学基金

摘　　要：本文调查我国东北和中南4个城市1161例反复发作肢体淤斑和/或月经过多者,各例的血小板计数、出血时间、凝血象和ADP、肾上腺素诱导血小板的聚集功能均正常,其中仅对SJAMP诱导的聚集缺陷者共219例,其异常率18.9％。女性149例,男性70例,年龄2～73岁,平均31岁.本文调查结果认为本病在临床上并不少见.我们同时又修改了本病的诊断指标,改称本病为SJAMP诱导聚集缺陷症.This investigation presents cases of 1161 patients with repeated occurrence of ecchymosis on extremities and/or menorrhagia from four cities of the Chinese East-North and Centro-South. As they all have normal blood platelet counts and normal results of coagulation profiles and platelet aggregation induced by ADP and epinephrine. Among these patients, 219 cases failed in SJAMP-induced platelet aggregation, the abnormality rate being 18.9% 149 were female and 70 male,ranged in age from 2 to 73 years with an average of 31. Our study is likely to reveal that the incidence of this disease is still relatively common in clinical practise than is generally believed. And we propose to revise the diagnostic criteria and to term SJAMP-induced platelet aggregation defect.

关 键 词：刺参酸性粘多糖 血小板聚集 

分 类 号：R55[医药卫生—血液循环系统疾病]