冠状动脉血流储备测量方法的研究进展  

Progress of Method to Measure Coronary Flow Reserve

作　　者：陈红磊 廉哲勋[2] 

机构地区：[1]青岛市城阳区人民医院心内科,山东青岛266109 [2]青岛大学医学院附属医院心内科,山东青岛266003

出　　处：《心血管病学进展》2009年第B04期25-27,共3页Advances in Cardiovascular Diseases

摘　　要：冠状动脉血流储备为冠状动脉最大舒张时的血流量与静息状态下的血流量的比值,可用于评价冠状动脉狭窄的生理学意义及估计血管重建的充分性,为冠心病介入治疗的选择和预后的判断提供重要信息。多普勒超声技术最早用于测定冠状动脉血流储备,通过测定冠状动脉的静息相和充血相时间平均峰值流速来计算。正电子发射体层摄影为非有创方法定量测定心肌血流和血流储备。近年来TI MI研究组发展了TI MI计帧法评价冠状动脉血流和计算血流储备。今后应着重对冠状动脉血流储备的参考值标准化,以便更好地对冠状动脉疾病进行评价。Coronary flow reserve was the ratio of coronary flow volume in maximum relaxation to in rest state, to assess the physiology of coronary artery stenosis and estimate the sufficiency of vascular reconstruction, and to provide important information for the intervention of coronary artery disease and prognosis determination. Doppler uhrosonic technology was used earlier to assess coronary flow reserve, by measuring the time-averaged peak velocity in rest and hyperemia to calculate coronary flow reserve. Positron emission tomography was an no-invasive method to measure myocardial flow and flow reserve quantitatively. In recent years,TIMI group developed a new method-TIMI frame count to assess coronary flow and determine coronary flow reserve. Hereafter,the most important work is to standardize the reference value of coronary flow reserve, so as to assess coronary artery disease conveniently.

关 键 词：冠状动脉血流储备 多普勒超声技术 正电子发射体层摄影 TIMI计帧法 

分 类 号：R541.4[医药卫生—心血管疾病]