新仿牛黄的抗惊厥作用  

anticonvulsion effect of the New Imitate Calculus Bovis

作　　者：于瑞起[1] 邹玲 金润[1] 谢静波 赵德永[3] 

机构地区：[1]北京长城制药厂 [2]北京市肿瘤防治办公室 [3]北京市药品检验所

出　　处：《中药药理与临床》1989年第2期38-39,共2页Pharmacology and Clinics of Chinese Materia Medica

摘　　要：牛黄为脊椎动物哺乳纲牛科牛BostaursdomesticusGmelin的胆结石。由于天然牛黄极为短缺,价格昂贵,因而许多学者都在进行人工牛黄的研究。五十年代,唐德煊首先进行了人工合成牛黄的研究并获得成功。后经朱颜进行的药理实验表明,人工牛黄对古柯碱和咖啡碱引起的小鼠惊厥有对抗作用,此点与天然牛黄的药理作用是一致的。1971年,卫生部组织了人工牛黄药理实验协作小组进行了实验,观察到人工牛黄对戊四氮引起的小鼠惊厥也有较好的对抗作用。同年年底。The anticonvulsion effect of New Imitate Calculus Bovis to be made according to the main chemical composition and ratio of the Calculus Bovis on the mice caused by the Pen-tetrazol was studied. The result showed New Imitate Calculus Bovis has obviously anticonvulsion effect,it is in accord with the literature recorded the Caculus Bovis. The result also suggests that New Imitate Calculus Bovis may substitute for the Calculus Bovis in the useness of clinic and pharmacy industry.

关 键 词：NEW IMITATE CALCULUS BOVIS CALCULUS BOVIS Anticonvulsion 

分 类 号：R28[医药卫生—中药学]