向附睾注射不同剂量鱼肝油酸钠与精子计数关系的研究  

STUDY ON THE RELATIONSHIP BETWEEN DIFFERENT DOSES OF SODIUM MORRHATE AND THE SPERM COUNT

作　　者：张富平[1] 谢文英[1] 吴明章[1] 骆毅 王一飞[1] 

机构地区：[1]上海第二医科大学组织胚胎教研室 [2]云南省计划生育科学技术指导所

出　　处：《中国男科学杂志》1989年第1期9-11,共3页Chinese Journal of Andrology

摘　　要：本文对家兔及人进行了向附睾注射不同剂量的鱼肝油酸钠(SM)与精子计数变化关系的研究。结果表明:向家兔附睾每侧注射SM0.1ml时,6周后4例家兔精子计数全部恢复正常;0.3ml时,10周后10例家兔中4例精子计数恢复正常;当每侧注射0.6ml时,在4个月及9个月各4例家兔观察中,精子计数均未恢复正常,为无精或少精。此外10例志愿者向附睾每侧注射0.5ml后,在术后12个月精子计数观察中,2例计数为6～7×10~6/ml外,其余仍为无精和少精。因此我们认为注射不同剂量的SM能引起不同的精子计数改变。The relationship between the doses of sodium morrhuate(SM) and the sperm count was studied. Four rabbits received 0.1ml per side had their sperm counts recovered in 6 weeks,SM 0.3ml per side were given to 10 rabbits and among them 4 recovered 10 weeks later. When the dose reached 0.6 ml per side, there was no tendency of recovery in 8 rabbits 4 and 9 months after injection.In 10 healthy volunteers, SM 0.5 ml per side were given. The sperm counts in 2 were 6～8×10~6/ml, whereas the rest remained azoospermic 12 months after injection.These results indicate that the antifertlity effect of SM is closely related to the dose employed.

关 键 词：鱼肝油酸钠 精子计数 

分 类 号：R697[医药卫生—泌尿科学]