A NEW METHOD UTILIZED TO DETECT DNA SINGLE STRAND BREAK(NICK-TRANSLATION)  

作　　者：刘杰 杨胜利 胥彬 

机构地区：[1]Shanghai Institute of Materia Medica, Academia Sinica

出　　处：《Chinese Science Bulletin》1989年第13期1130-1133,共4页

摘　　要：It is often needed to detect the DNA single strand break in biological studies. The four most frequently used methods are alkaline elution, alkaline sucrose gradient sedimentation, hydroxyapatite chromatography and nucleoid sedimentation. All these are not perfect because of a number of disadvantages, such as

关 键 词：DNA SINGLE STRAND BREAK nick-translation 10-hydroxyeamptothecin 

分 类 号：N[自然科学总论]