肱动脉内皮功能、颈动脉内膜-中层厚度及踝臂指数与冠心病的相关性研究  

Clinical Study on Correlations of Brachial Artery Endothelial Function, Carotid Intima-midia Thickness and Ankle-brachial Index

作　　者：马仁子[1] 夏稻子[1] 

机构地区：[1]大连医科大学附属第二医院超声科,辽宁省大连市116027

出　　处：《中国超声医学杂志》2009年第4期389-391,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨肱动脉内皮依赖性舒张功能（EDD）、颈动脉内膜-中层厚度（I MTc）及踝臂指数（ABI）与冠心病的相关性研究。方法选择中老年对照组41例,心绞痛组38例,心肌梗死（心梗）组40例,使用彩色多普勒超声仪检测肱动脉在静息、反应性充血后舒张末内径的变化,并测量I MTc,用普通血压计分别测量并计算三组踝臂指数,同时采集患者血液生化、心电图、病史、超声及冠脉造影等各项指标。结果EDD%：心梗组、心绞痛组、对照组呈递增趋势（P〈0.05）,I MTc：心梗组、心绞痛组、对照组呈递减趋势（P〈0.05）,ABI〈0.9的百分率：心梗组、心绞痛组、对照组呈递减趋势（P〈0.05）。结论EDD、I MTc、ABI与冠心病缺血的严重程度有一定的相关性。Objective To evaluate the correlation of brachial-artery endothelia dependent dilation （EDD）, carotid intima-midia thickness （IMTc） and ankle-brachial index （ABI）. Methods 42 middle-elder healthy people, 36 coronary heart disease patients with angina pectoris （AP） and 40 patients with myocardial infarction （MI） were employed for measuring the baseline inner diameters of the humeral artery diameters after reactive hyperemia and IMTc, using high resolusion ultrasound and measuring ABI of three groups by blood pressometer, all the patients underwent hemostetic factors evaluation, ECG, history collection, ultrsound and coronary angiography et al. Results EDD~ in AP group is higher than that in MI group and lower than that in nomal control （P〈0.05）, IMTc in AP group is thinner than that in MI group and thicker than that in normal control （P〈0.05）, the ratio of ABI〈0.9 in AP group is higher than that in MI group, and lower than that in healthy volenteers （P〈0.05）. Conclusions Coronary heart disease is correlated with EDD, IMTc and ABI.

关 键 词：内皮依赖性舒张 内膜-中层厚度 踝臂指数 彩色多普勒超声 

分 类 号：R587.2[医药卫生—内分泌] R725.97[医药卫生—内科学]