伪狂犬病基因缺失疫苗的研究进展  

The Progress of Gene-deleted Vaccine against Pseudorabies Virus

作　　者：凌宗帅[1] 郭文龙[2] 刘冠华[2] 马荣德[2] 阎振贵[2] 

机构地区：[1]济南出入境检验检疫局,济南250014 [2]山东农业大学动物科技学院,泰安271018

出　　处：《生物技术通报》2009年第4期25-28,共4页Biotechnology Bulletin

摘　　要：伪狂犬病是由疱疹病毒科伪狂犬病病毒引起的多种畜、禽及野生动物的一种急性传染病。动物感染后表现为从隐性临床症状到严重的呼吸道和神经症状综合症。该病给世界养猪业造成巨大的损失,目前预防该病主要是以疫苗接种为主。综述了当今广泛应用的伪狂犬病基因缺失疫苗的研究现状和进展。Pseudorabies is caused by Pseudorabies virus （PRV） which is a member of family herpesviridae and is the agent of acute infectious disease in domestic and wild animals. Infection may result in signs ranging from clinically inapparent latent carrier states to fatal respiratory tract or neurologic disease syndromes. The virus is responsible for major economic loss in pig industries. Vaccination is one of the most effective prophylactic measure to prevent the disease. In this assay, research progress of PRV gene- deleted vaccine that has been used extensively was discussed.

关 键 词：伪狂犬病病毒 基因缺失疫苗 进展 

分 类 号：S852.5[农业科学—基础兽医学]