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作 者:唐可[1] 武百山[1] 何明伟[1] 杨立强[1] 倪家骧[1]
机构地区:[1]首都医科大学宣武医院疼痛科,北京100053
出 处:《疑难病杂志》2009年第4期211-213,共3页Chinese Journal of Difficult and Complicated Cases
基 金:北京市科技计划项目(No.Y0204003040631)
摘 要:目的探讨在CT引导下经硬膜前间隙治疗腰椎间盘突出症的临床疗效。方法78例腰椎间盘突出症患者随机分为2组:A组(40例)连续硬膜外腔前间隙镇痛后行胶原酶溶解,B组(38例)单行连续硬膜外腔前间隙镇痛。治疗后1周、3个月、12个月对2组患者疗效进行随访。结果2组治疗后1周、3个月、12个月VAS值均较治疗前明显降低(P<0.01);A组治疗后12个月VAS值较B组明显改善(P<0.05)。A组、B组术后12个月改良Macnab疗效评定差异有统计学意义(P<0.05),有效率分别为95.0%、89.5%,A组疗效优于B组。结论在CT引导下经硬膜前间隙连续镇痛联合胶原酶溶解术治疗腰椎间盘突出症远期疗效优于单行连续硬膜外腔镇痛。Objective To explore the clinical effect of continuing anesthesia from anterior epidural space combined with chemmonucleolysis with collagenase for treating patients with lmnber disc herniation. Methods 78 patients with hunber disc herniation were randomly divided into combining group (group A,40 cases) and anesthesia group (group B, 38 cases). The effect was assessed 1 week, 3 months, 12 months after treatment. Results The value of VAS in two groups at 1 week , 3 and 12 months after treatment were re,narkably lower than that before treatment ( P 〈 0.01). Compared with those in the group B, VAS scores and Macnab assessment in group A were significantly improved at 12 months after treatment ( P 〈 0.05). The effective rate at 12 months were 95.0%, 89.5 % in group A and B respectively. Conclusion The long-tern1 effect of therapy of continuing anesthesia from anterior epidural space combined with eollagenase for treating patients with LDH was better than anesthesia alone.
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