TDP联合辣椒碱软膏外敷治疗类风湿关节炎的护理研究  

Study on nursing of rheumatoid arthritis patients treated with TDP combined with capsaicin

作　　者：宋静[1] 

机构地区：[1]山东省枣庄市立医院,277101

出　　处：《国际护理学杂志》2009年第4期446-448,共3页international journal of nursing

基　　金：枣庄市科技局科研立项项目2008（076）

摘　　要：目的研究TDP联合辣椒碱软膏外敷与慢作用抗风湿药治疗活动性类风湿关节炎的局部关节肿痛症状、疗效及安全性。方法80例患者随机分为观察组和对照组，每组40例。观察组采用TDP联合辣椒碱软膏加常规抗风湿药，对照组仅采用常规抗风湿药，两组患者均常规护理。比较观察两组患者压痛关节数、肿胀关节数、晨僵时间、护士评分、患者评分及血沉、c反应蛋白的改善及不良反应发生的情况。结果两组患者治疗前后肿胀关节数、压痛关节数、患者评分、护士评分、晨僵时间、血沉、C反应蛋白具有显著性差异（P〈0．01）。观察组与对照组治疗前后比较具有显著性差异（P〈0．01）。两组差值比较有显著性差异（P〈0．05），观察组各项疗效指标改善优于对照组。两组均无严重不良反应的发生。结论TDP联合辣椒碱软膏外敷治疗类风湿关节炎，明显减轻关节肿痛，关节功能明显改善且安全有效。Objective To investigate the efficacy and safety of TDP combined with topical capsaicin cream in treatment of joint pain or swelling in patients with active rheumatoid arthritis. Methods 80 patients with active rheumatoid arthritis were divided into observation group （ n = 40） and control group （ n = 40） randomly. In the observation group, TDP, eapsaicin and slow acting antirheumatie drugs （ metbotrexate ＋ sulfasalazine） were given. The routine antirheumatie drugs were given in the control group. The two groups were both given routine nursing. Tender joint count, swollen joint count, morning stiffness, nurse global assessment, patients global assessment, erythroeyte sedimentation rate （ESR） and C - reactive protein （CRP） were observed. Simultaneously, the adverse reactions were recorded. Results All the indices had been improved significantly after treated in both groups （P 〈 0. 01 ） . The indices in observation group were better than those in control group （ P 〈 0.05 ） . Severe adverse reactions was not occurred in the two groups. Conclusions TDP combined with capsaicin cream is effective and safe in treatment of joint pain or swelling in patients with active rheumatoid arthritis. It can alleviate joint pain or swelling and improve joint function.

关 键 词：类风湿关节炎 TDP 辣椒碱 护理 

分 类 号：R473.5[医药卫生—护理学]