连续动态血糖监测在2型糖尿病中的临床价值  

Drift of glucose in patients withT2DM with continuous glucose monitoring system

作　　者：穆亚东[1] 

机构地区：[1]河南省商丘市第一人民医院内分泌科,476000

出　　处：《中国实用医药》2009年第10期20-21,共2页China Practical Medicine

摘　　要：目的应用动态血糖监测系统(CGMS)研究2型糖尿病(T2DM)强化治疗过程中低血糖发生的特征。方法采用动态血糖监测系统(CGMS)对50例使用胰岛素治疗的HbA1c<7.0%的2型糖尿患者进行连续3 d的血糖监测。结果本组患者血糖≤2.8 mmol/L(低血糖)占3.3%,但以21:00～24:00最多,0～3:00点次之。血糖在2.9～7.8 mmol/L之间占71.3%,血糖在2.9～10.0 mmol/L之间占89%,血糖>10 mmol/L(血糖控制不良)占7.7%,各时段均能见到,以6:00～12:00为多。探头监测到低血糖患者27例,低血糖的发生率为54.0%(27/50)。21:00～3:00(定义为夜间)低血糖的发生率为66.7%(18/27)。结论CGMS能及时准确地发现低血糖,了解低血糖的影响因素及低血糖后的反应,以指导临床治疗,制定针对性的临床治疗方案。Objective To study drift of glucose in patients with type 2 diabetes mellitus（T2DM） with continuous glucose monitoring system（CGMS）. Methods 50 cases people with type 2 diabetes of HbAlc 〈 7. 0% of insulin therapy were given continuous glucose monitoring for 3 d with continuous glucose monitoring system （CGMS）. Results Patients of this group, blood glucose ≤ 2. 8 mInol/L （low blood sugar） accounted for 3.3 percent, but the most at 21：00 - 24：00, followed by 0 - 3：00. Glucose in the 2. 9 - 7. 8 mmol / L accounted for between 71.3%, blood glucose in the 2. 9 -10.0 mmol / L accounted for 89%, blood glucose 〉 10 mmol/L （blood glucose control undesirable） accounted for 7.7%, can be seen at any time the most at 6：00 - 12：00 points. Probe monitored 27 cases of patients with hypoglycemia, the incidence of hypoglycemia was 54.0% （27/50）. 21：00 - 3：00 （ defined as night） the incidence of hypoglycemia was 66. 7% （18/27）. Conclusion CGMS reflects the characteristic of hypoglycemia accurately and offers valuable information for us about clinical therapy.

关 键 词：2型糖尿病 动态血糖监测系统 胰岛素 糖化血红蛋白 

分 类 号：R587.1[医药卫生—内分泌] R734.2[医药卫生—内科学]