晚期肺癌患者深部真菌医院感染75例临床分析  

Hospital-acquired Deep Fungal Infection in Advanced Lung Cancer Patients:Status and Analysis of 75 Cases

作　　者：刘丽娟[1] 亓久德[1] 亓瑞先[1] 

机构地区：[1]莱芜市人民医院检验科,山东莱芜271100

出　　处：《中华医院感染学杂志》2009年第7期778-780,共3页Chinese Journal of Nosocomiology

摘　　要：目的调查晚期肺癌患者深部真菌感染现状,探讨其预防及控制措施。方法回顾调查2003年5月-2007年7月晚期肺癌患者并深部真菌感染的临床资料,对真菌感染的菌种构成、感染部位及高危因素进行单因素分析。结果75例真菌感染以下呼吸道感染为主,占65.3%,其次为口腔,占14.7%;各种感染标本培养出真菌82株,以白色假丝酵母菌为主,占53.7%,其次为近平滑假丝酵母菌14.6%。结论深部真菌感染有上升趋势,其原因与肺癌患者原发病,外周血白细胞、侵入性操作、年龄及抗菌药物的应用等因素密切相关。OBJECTIVE To investigate the situation of hospital-acquired fungal infection of 75 cases with advaced lung cancer patients. METHODS The clinical information of deep fungal infection in 75 advanced lung cancer patients was investigated. The risk factors, the site and species were analyzed. RESULTS The lower respiratory tract and oral imfections accounted for 65.3% and 114.6% in 75 cases with deep fungai infections. Eighty-two stranins were isolated from various clinical specimens, in which Candida ailbicans and C. palasilosis accounted for 53.7 % and 14.6%, respectively. CONCLUSIONS The rate of the deep fungal infection in advanced lung cancer patients is increasing. It is related to primary tumor, the amounts of white cells, invasive operation, age and use of antibiotics.

关 键 词：晚期肺癌 深部真菌 感染部位 

分 类 号：R379[医药卫生—病原生物学]