经皮肾镜取石术中肾盂尿培养与血浆内毒素测定的临床意义  

Renal Pelvic Urine Culture and Plasma Endotoxin Detection for Patients Underwent Percutaneous Nephrolithotomy

作　　者：蓝志相[1] 卢秋维[2] 梁亮[2] 梁建波[1] 王晓平[1] 刘刚[1] 玉海[1] 

机构地区：[1]广西壮族自治区人民医院泌尿外科,广西南宁530021 [2]广西壮族自治区人民医院检验科,广西南宁530021

出　　处：《中华医院感染学杂志》2009年第7期795-797,共3页Chinese Journal of Nosocomiology

基　　金：广西壮族自治区卫生厅课题(Z2006166)

摘　　要：目的探讨经皮肾镜取石术(PCNL)中肾盂尿培养与血浆内毒素水平测定的临床价值。方法对50例PCNL治疗肾结石患者进行术中肾盂尿培养和术前、术后血浆内毒素水平测定。结果术后发热13例,发生率为26.0%;术中肾盂尿培养阳性7例,阳性率14.0%;术前、术后血浆内毒素水平分别为(0.11±0.03)EU/ml、(1.95±0.52)EU/ml,差异有统计学意义(P<0.05);术后血浆内毒素水平在术后发热患者和未发热患者中分别为(4.26±1.18)EU/ml(、1.13±0.44)EU/ml,差异有统计学意义(P<0.05)。结论PCNL中肾盂尿培养与血浆内毒素水平测定有助于判断术后发热的原因,有利于临床合理应用抗菌药物和及时对症处理。OBJECTIVE To investigate the value of pelvic： urine culture and plasma endotoxin detection for patients underwent percutaneous nephrolithotomy（PCNL）. METHODS A total of 50 patients underwent PCNL for kidney stone were retrospectively and prospectively analyzed. Intraoperative pelvic urine culture, detection of pre-and postoperative plasma endotoxin were carried out in all patients. RESULTS Among the 50 patients, 13 patients showed fever after PCNL（26.0%） and pelvic urine culture showed positive in 7 cases （14.0%）. Pre- and post-operative plasma endotoxin was（0.11 ± 0.03） EU/ml and （1. 95 ± 0. 52） EU/ml, respectively（P〈0. 05）. Post-operative plasma endotoxin in fever group and non-fever group was （4. 26 ± 1. 18） EU/ml and （1. 13 ±0. 44） EU/ml, respectively （P〈 0. 05）. CONCLUSIONS Pelvic urine culture and plasma endotoxin detection for patients underwent PCNL are helpful for estimation of the reason of the postoperation fever. They are also helpful for rational selection of antibacterials and symptomatic treatment on time.

关 键 词：经皮.肾镜取石术 感染 内毒素 尿培养 

分 类 号：R446.12[医药卫生—诊断学]