急性胰腺炎患者的甲襞微循环观察  

Observation on nailfold microcirculation in patients with acute pancreatitis

作　　者：梁琪[1] 王红[1] 任爱民[1] 张丽霞[1] 田瑛[1] 张淑文[1] 

机构地区：[1]首都医科大学北京友谊医院感染暨急救医学科,北京100050

出　　处：《临床和实验医学杂志》2009年第4期25-26,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨急性胰腺炎与甲襞微循环变化之间的关系,评价甲襞微循环检测对判定急性胰腺炎的病情轻重及治疗转归的作用。方法本院急性胰腺炎患者69例及对照组30例,分别观察甲襞微循环形态、微血流动态、袢周状态3个方面共16项指标,并应用微循环图像处理软件,对观测结果进行分析。结果急性胰腺炎患者出现甲襞微循环障碍占66.7%,其中重度异常占17.40%,中度异常占23.91%,轻度异常占58.70%,与对照组比较有显著性差异(P<0.05)。结论微循环障碍与急性胰腺炎病程及进展有关,提示临床早期改善微循环,对急性胰腺炎治疗效果有积极意义。Objective To investigate the relationship between acute pancreatitis and changes of nailfold microcirculatian and to evaluate the significance of changes in nailfold microcirculation for judgment of the severity of acute pancreatitis and clinical outcome. Methods Altogether 16 indices including patterns of nailfold microcirculation, dynamics of micro - blood flow and loop status had been observed in 69 patients with acute pancreatitis and 30 normal controls. The results of observation were analyzed by using a microcirculatory image processing software. Results Dysfunction in nailfold microcirculation was found in 66.7% of patients with acute pancreatitis. 17.40% of these positive cases were severely abnormal, 23.91% of them were moderately abnormal, and 58.70% were mildly abnormal. There was significant difference between trial group and controls （ P 〈 0.05）. Conclusion Microcirculatory dysfunction is related to the pathogenesis and development of acute pancreatitis. This study suggested that improvement of microciroulation in early clinical course will be beneficial to the treatment of acute pancreatitis.

关 键 词：急性胰腺炎 甲襞微循环 关系 

分 类 号：R657.51[医药卫生—外科学]