单涎酸神经节苷脂对急性脑梗死的治疗  

Clinical Effects of Ganglioside on Acute Cerebral Infarction

作　　者：吕希峰 董晓辉 

机构地区：[1]山东省胶州市人民医院,266300

出　　处：《青岛医药卫生》2009年第2期96-97,共2页Qingdao Medical Journal

摘　　要：目的研究单涎酸神经节苷脂对急性脑梗死的治疗效果。方法将40例脑梗死患者随机分为两组,治疗组给予神经节苷脂治疗,对照组给予吡拉西坦治疗。15天后对两组病人进行神经功能缺损程度(NDS)评分并比较。结果治疗前两组NDS评分无显著性差异。治疗后治疗组与对照组比较,NDS评分、NDS减少值、有效率比较均P<0.01。结论脑梗死急性期应用神经节苷脂治疗能够减轻患者的神经功能缺损程度,提高患者神经功能和生活质量。Objective To observe the clinical effects of ganglioside GM1 on acute cerebral infarction. Methods Forty patients with acute cerebral infarction were randomly and equally divided into the control group and the experiment group. The experiment group was treated with ganglioside while the control group was treated with Piracetam. After 15 days neurological deficit scale （NDS） was valued and corn pared. Results There was no significant difference of NDS between two groups before treatment. After treatment, NDS score, the value of NDS reduce and the efficiency between the treatment group and the control group were all significantly different（P〈0.01）. Conclusion Application of ganglioside treatment in acute phase cerebral infarction can relieve the neurological disfunetion and improve quality of life.

关 键 词：单涎酸神经节苷脂 脑梗死 急性期 

分 类 号：R473.3[医药卫生—护理学]