COPD时下呼吸道感染的细菌学变化  

On Change of Bacteriology in Lower Respiratory Tract Infections With COPD

作　　者：钟献年[1] 邓哲彤[2] 

机构地区：[1]广东药学院内科,广州510224 [2]广州市红十字会医院内科,广州510224

出　　处：《广东药学院学报》1998年第1期15-17,共3页Academic Journal of Guangdong College of Pharmacy

摘　　要：调查近十年来广州地区COPD患者下呼吸道细菌感染的菌群变化。先用3％双氧水漱口，清晨留第二口痰作细菌培养。根据细菌的形态、生化反应和血清学变化作细菌鉴定。以420例COPD患者为对象，对2040份痰标本的细菌生长情况作对比性分析，并对280例次培养的细菌作药物敏感试验（采用单片纸碟法）。结果表明，在有细菌生长的983例次的标本中，G-杆菌科372例（占37．8％），G+球菌属300例（占30．5％），假单胞菌属215例（21．8％），人院前以G+细菌感染为主，而入院后则以G-杆菌感染占多数，尤其是绿脓杆菌。表明本地区COPD患者的下呼吸道感染，G-杆菌超过G+球菌，绿脓杆菌感染有日益增多的趋势，应引起临床的重视。To investigate the change of bactericlogy in the lower respiratory tract infections with COPD in Guangzhou district in recent ten years, and from 420 cases of COPD,200 sputum specimens were determined and 280 cases of positive sputum specimens were subjected to sensitive test of pharmacology, then, the results were analysed comparatively. 983 of the 2040 specimens had a definite bacteriologic growth, in which 372 cases were gram-negative bacilli (37. 8%), 300 cases grampositive cocei (30. 5% ) and 215 cases pseudomonas aeruginosa (21. 8%). The grain-negative bacilli infections were much more than the gram-positive cocei in post-hospitalization but much less in prehospitalization. This founding revealed that gram-negative bacilli infections were predominant and the pseudomonas aerugionosa infections were increasing gradually in the lower respiratory tract infections.

关 键 词：细菌学 肺疾病 阻塞性肺疾病 下呼吸道感染 

分 类 号：R563.05[医药卫生—呼吸系统] R446.5[医药卫生—内科学]