动脉吻合区肽能神经变化的实验研究  

Reinnervation of NPY,CGRP nerves in anastomosis site of rat saphenous artery

作　　者：许家军[1,2] 陈尔瑜[1,2] 章玲[1,2] 余汇洋[1,2] 

机构地区：[1]上海市第二军医大学解剖学教研室 [2]第三军医大学

出　　处：《中国临床解剖学杂志》1998年第2期164-166,共3页Chinese Journal of Clinical Anatomy

基　　金：国家自然科学基金

摘　　要：目的：了解小血管吻合区的神经变化。方法：雄性ＳＤ大鼠１１只，在吻合大鼠隐动脉或剥除长约１０ｍｍ的隐动脉外膜后，用ＡＢＣ法作隐动脉手术区的ＮＰＹ、ＣＧＰＲ的免疫组织化学反应。结果：术后３ｄ动脉吻合区或单纯动脉外膜剥除区未见上述两类肽能神经。术后１４ｄ肽能神经已由术区两端进入术区。术后３０ｄ术区肽能神经的数量与形态与正常相似。结论：吻合小血管时剥除外膜可损及局部肽能神经，其恢复时间较长。bjective: To study reinnervation at the anastomosis site of small blood vessels.Methods:ABC immunohistochemical method was used to show NPY and CGRP at the anastomosis site or at the region with 10 mm long adventitia stripped saphenous artery in 11 rats.Results:Three days after surgery,NPY and CGRP nerves were not seen in the surgical site.Neuropetide nerves came into the surgical site from both ends in fourteen days,and reached to normal morphology in thirty days.Conclusions: Stripping the adventitia of small blood vessels during anastomosis damages the neuropeptide nerves at the surgical site.Reinnervation in small blood vessel takes place slowly.

关 键 词：小动脉 吻合 神经肽 

分 类 号：R654.3[医药卫生—外科学] R338[医药卫生—临床医学]