葛枣猕猴桃叶化学成分的研究  

Studies on Chemical Constituents of the Leaves of Actinidia polygama

作　　者：陆娟[1] 崔贵军[2] 王秀英[1] 朱娜[1] 刘桂英[1] 李绪文[1] 金永日[1] 

机构地区：[1]吉林大学化学学院,长春130012 [2]长春师范学院人事处,长春130032

出　　处：《中国药学杂志》2009年第5期328-330,共3页Chinese Pharmaceutical Journal

摘　　要：目的对葛枣猕猴桃[Actinidia polygama(Sieb. et Zucc.)Miq]叶的化学成分进行分离鉴定。方法利用多种色谱手段对化学成分分离纯化,利用ESI-MS、1H-NMR、13C-NMR等光谱数据鉴定其结构。结果分离得到8个单体化合物,分别鉴定为:山柰酚(Ⅰ),胡萝卜苷(Ⅱ),伞形花内酯(Ⅲ),山柰酚-3-O-β-D-吡喃半乳糖苷(Ⅳ),异鼠李素-3-O-β-D-吡喃葡萄糖苷(Ⅴ),山柰酚-3-O-α-L-鼠李糖基-(1→6)-β-D-吡喃半乳糖苷(Ⅵ),芹菜素-6-C-葡萄糖基-8-C-木糖苷(Ⅶ),山柰酚-3-O-α-L-鼠李糖基-(1→3)-α-L-鼠李糖基-(1→6)-β-D-吡喃半乳糖苷(Ⅷ)。结论化合物Ⅰ-Ⅷ均是首次从该植物中得到。OBJECTIVE To separate and identify the chemical constituents of the leaves ofActinidiapolygama （Sieb. et Zucc.） Miq. METHODS Multi-chromatographic methods were used for the isolation and purification. Structures were elucidated on the basis of spectroscopic data analysis including ESI-MS, 1H-NMR and 13C-NMR. RESULTS Eight compounds were isolated and identified as kaempferol（ Ⅰ ）, daucosterol（ Ⅱ ）, umbelliferone（Ⅲ）, kaempferol-3-O-β-D-galactopyranoside（Ⅳ）, isorhamnetin-3-O-β- D-glucoside（V）, kaemp-ferol-3-O-a-L-rhamnopyranosy-（1-→6）-β-D-galactopyranoside（Ⅵ）, 6-C-glycopyranosyl-8-C-xyloeyl apigenin （Ⅶ）, kaempferol- 3-O-α-L-rhamnpyranosyl-（1→3）-α-L-rhamn-opyranosyl-（1→6）-β-D-galactopyranoside（Ⅷ）. CONCLUSION Compotmd Ⅰ- Ⅶ were isolated from the leaves of Actinidiapolygama for the first time.

关 键 词：葛枣猕猴桃 猕猴桃科 化学成分 

分 类 号：R248.1[医药卫生—中医临床基础]