急性呼吸道感染患儿人类博卡病毒检测与分析  

Human Bocavirus in Children with Acute Respiratory Tract Infections

作　　者：伍严安[1] 曾秀雅[1] 周建林[1] 付希[1] 陈发林[1] 陈发文[1] 

机构地区：[1]福建医科大学省立临床医学院,福建省立医院检验科,福州350001

出　　处：《福建医科大学学报》2009年第2期159-162,共4页Journal of Fujian Medical University

基　　金：福建省自然科学基金资助项目(F0310042)

摘　　要：目的探讨人类博卡病毒(HBoV)与儿童急性呼吸道感染(ARTI)的关系。方法RT-PCR检测2006年11月-2008年4月连续2个冬春季儿科418例呼吸道感染鼻咽分泌物标本的HBoV。结果HBoV阳性率为5.0%(21/418)。阳性者年龄在4月～5岁。下呼吸道感染HBoV阳性率11.1%(17/153)显著高于上呼吸道感染的1.5%(4/265)(χ2=18.741,P<0.001)。结论HBoV是本地区冬春季儿童呼吸道感染、尤其是下呼吸道感染的的重要病原之一。Objective To investigate the prevalence of human bocavirus （HBoV） in children with acute respiratory tract infections （ARTI）. Methods HBoV was detected by reverse transcription polymerase chain reaction （RT-PCR） in nasopharyngeal swab samples from 418 pediatric patients with ARTI during 2 consecutive winter-spring seasons from December 2006 to April 2008 in Fuzhou area. Results Twenty-one of 418（5%） samples were positive for HBoV. All of the positive specimens were from children aged between 4 months and 5 years. The positive rate was significantly higher in lower respiratory tract infections than in upper respiratory tract infections （11. 1% vs 1.5%, χ^2 -= 18. 741, P〈0. 01）. Conclusion HBoV is an important pathogen in ARTI especially in lower respiratory tract infections in Fuzhou area.

关 键 词：呼吸道感染 急性病 聚合酶链反应 细小病毒B19 人 细小病毒科感染 福州 

分 类 号：R725.129.9[医药卫生—儿科] R373.19[医药卫生—临床医学]