保妇康栓治疗伴有人乳头瘤病毒感染的宫颈上皮内瘤Ⅰ型38例  

Baofukang Suppository in the Treatment of Cervical Intraepithelial Neoplasia Ⅰ Complicated with Human Papilloma Virus Infection:A Report of 38 Cases

作　　者：沈丹[1] 左艳[1] 闫彩平[1] 

机构地区：[1]暨南大学医学院第三附属医院,广东珠海519000

出　　处：《安徽中医学院学报》2009年第2期17-19,共3页Journal of Anhui Traditional Chinese Medical College

摘　　要：目的:观察中药保妇康栓治疗伴有人乳头瘤病毒(human papilloma virus,HPV)感染的宫颈上皮内瘤(cervical intraepithelial neoplasia,CIN)Ⅰ型患者的临床疗效。方法:伴有HPV感染的CINⅠ型76例患者被随机分成治疗组和对照组。治疗组予中药保妇康栓阴道内置药3个月,治疗后行液基细胞学检查(liquid based cytology test,LCT)及电子阴道镜检查。对照组不使用任何药物,3个月后行LCT及电子阴道镜检查。结果:3个月后LCT示治疗组HPV感染转阴率为71.05%,与对照组自然消退率(50.00%)比较,差异具有显著性(P<0.05)。电子阴道镜检查示治疗组55.27%的CINⅠ型转为慢性炎症,与对照组(34.21%)比较,差异具有显著性(P<0.05),结论:保妇康栓对轻度宫颈病变有一定的治疗作用。Objective：To observe the clinical effects of Baofukang Suppository in women with cervical intraepithelial neoplasia I （CIN Ⅰ ） complicated with human papilloma virus （HPV） infection. Methods： Seventy-six patients were randomly divided into two groups： treatment group （treated with Baofukang Suppositories for 3 months） and control group （no intervention measures were taken）. Three months later, liquid-based cytology （LCT） and electric colposcopy were employed to evaluate the HPV infection and the lesion, respectively. Results： The negative conversion rate of HPV infection in treatment group was 71. 05%, being significantly higher than 50.00% in control group （P〈0.05）. Electric colposcopy showed that 55.27% patients with CIN Ⅰ developed chronic cervicitis in treatment group , being significantly higher than 34.21% in control group （P〈0.05）. Conclusion： Baofukang Suppositories has some therapeutic effects in treating mild cervical diseases.

关 键 词：宫颈上皮内瘤 HPV感染 保妇康 

分 类 号：R271.11[医药卫生—中医妇科学] R285.5[医药卫生—中医学]