一株H5N1亚型高致病力禽流感病毒人工感染鸭的18项血液生化指标测定  

Eighteen Blood Biochemical Indexes Assay of Ducks Experimentally Infected with a Highly Pathogenic Avian Influenza Virus,A/duck/Guangdong/220/2004(H5N1)

作　　者：李玉谷[1] 崔聪颖[1] 周泉鹤[1] 叶远兰[1] 马勇江[1] 张媛[1] 李楚宣[1] 

机构地区：[1]华南农业大学兽医学院,广州510642

出　　处：《中国畜牧兽医》2009年第4期36-42,共7页China Animal Husbandry & Veterinary Medicine

基　　金：广东省科技攻关项目(2004A2090102);广东省教育厅科学基金项目(Z02003)

摘　　要：鸭接种高致病力禽流感病毒A/duck/Guangdong/220/2004(H5N1)后,血清中的丙氨酸氨基转移酶(谷丙转氨酶)、天门冬氨酸氨基转移酶(谷草转氨酶)、γ-谷氨酰基转移酶、肌酸激酶和乳酸脱氢酶明显升高;碱性磷酸酶明显下降;α-淀粉酶先升高后下降;总蛋白、球蛋白、尿素氮、胆固醇、钙和磷轻微升高;白蛋白、肌酐、葡萄糖、甘油三酯和尿酸轻微下降。作者认为,检查这些血液生化指标的变化,对于诊断禽流感具有一定意义。Eighteen blood biochemical indexes were tested in ducks experimentally infected with a highly pathogenic avian influenza virus, A/duck/Guangdong/220/2004 （H5N1） by intravenous and eyes-nares-mouth-cloaca routes. The results showed that the activity or contents of serum alanine aminotransferase（glutamic-pyruvic transminase）, aspartate arninotrans ferase（glutamic oxaloacetic transminase）, γ-glutamyltransferase, creatine kinase, lactate dehydrogenase were significantly increased： alkaline phosphatase＇s were obviously decreased; early α-Amylase＇s were significantly increased, late slightly de creased; total protein, globin, urea nitrogen, cholesterol, calcium and phosphorus＇s were somewhat increased; albumin, creatinine, glucose, triglycerides and uric acid＇s were usually decreased. We consider that assaying these blood biochemical indexes are useful for diagnosing avian influenza.

关 键 词：H5N1亚型禽流感 血液生化 鸭 

分 类 号：S858.3[农业科学—临床兽医学]