心肌缺血预适应对缩小老年心肌梗塞范围的临床研究  被引量:1

TX Clinical study on the limitation of infarct size by ischemic preconditioning in aged patients with AMI

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作  者:高太有[1] 彭侃夫[1] 余洪军[1] 任国铨[1] 

机构地区:[1]济南军区总医院

出  处:《实用老年医学》1998年第1期17-18,共2页Practical Geriatrics

摘  要:目的探讨心肌缺血预适应对老年急性心肌梗塞(AMI)患者梗塞面积的影响。方法对照分析心肌梗塞前66例有心肌缺血预适应与44例无心肌缺血预适应老年AMI患者的临床资料。结果有心肌缺血预适应老年AMI患者其肌酸磷酸激酶(CPK)与肌酸磷酸激酶同功酶MB(CK-MB)峰值,复杂室性期前收缩、泵功能障碍发生率与近期死亡率等均显著低于无心肌缺血预适应老年AMI患者(P<0.01与P<0.05)。结论心肌缺血预适应有缩小老年心肌梗塞面积的作用,故对其近期预后可产生有益的影响。bjective The influence of ischemic preconditioning on the infarct size in aged patients with AMI was studied. Methods The clinical data of 66 elderly patients with ischemic preconditioning before AMI(group A)and 44 elderly patients suffering from AMI without ischemic preconditioning (group B) were comparatively analyzed. Results Peak levels of serum CPK and CPKMB,complex ventricular premature beats,incidence of cardiac pump function disturbance and shortterm mortality rate in group A were significantly lower than those in group B(P<001 or P<005). Conclusions Ischemic preconditioning can limit the infarct size,which may have good influence on the shortterm prognosis.

关 键 词:心肌缺血 预适应 心肌梗塞 老年人 

分 类 号:R542.2[医药卫生—心血管疾病]

 

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