背向散射积分技术在检测移植肾慢性排异反应中的应用价值  

Application of Utrasound Integrated Backscatter Measurement of Chronic Rejection Transplanted Kidney

作　　者：王峻松[1] 孟洁[1] 宋世洋[1] 

机构地区：[1]吉林大学第二医院,吉林长春130041

出　　处：《中国实验诊断学》2009年第4期513-515,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的应用背向散射积分技术检测移植肾脏疾病,并初步探讨背向散射积分技术在检测移植肾慢性排斥反应中的应用价值。方法将全部研究对象分为病例组和正常对照组,应用HP5500型超声诊断仪分别检测其肾脏的图像平均强度(AII)、图像峰-峰强度(PPI),并计算标化的背向散射积分(IBS%)、标化的图像峰-峰强度(PPI%),分别对各值进行分析比较。结果(1)病例组肾皮质IBS%值较正常对照组增高(P<0.05),PPI值、PPI%值较正常对照组增高,但无统计学意义。(2)病例组(②、③、④)随肾功能损害程度的加重,[肾皮质-肾髓质IBS%]值逐渐下降,与正常对照(①)组均存在差别,但均无统计学意义。结论(1)应用IBS技术可以实现超声对肾脏病变的定性、定量诊断。(2)IBS值可以反映移植肾脏慢性排异反应的声学改变。Objective To compare the IBS of renal cortex and medulla, and explore the clinical application of IBS quantifying transplanted kidney. Methods All the people divided into 2 groups： healthy person and patients, were analyzed with HP5500 sonograph. Average image intensity （AII）,peak to peak intensity（PPI） of renal were measured and normalized by IBS of renal sinus and expressed as IBS% ,PPI%. Results （ 1 ）IBS% of renal cortex and medulla, PPI renal medulla were both higher significantly in patients than those in control （ P 〈 0.05）. PPI,PPI% of renal cortex,PPI% renal medulla were higher in patients than those in control, but there were no significant difference. （2）With the aggravation of renal function,the value of [ cortex-medulla IBS% ]had a fradual decrease in patients. However, no significant difference was found among all the people. Conclusion （ 1 ） With the application of IBS rechifique, pathologic change of renal can be evaluated qualitatively and quantitatively. （2）IBS can reflect the echo change of renal.

关 键 词：背向散射积分 移植肾 排异反应 

分 类 号：R699.2[医药卫生—泌尿科学]