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作 者:徐茜[1] 柴栋[1] 孟谦谦[1] 聂继华[1] 童建[1] 曹毅[1]
机构地区:[1]苏州大学放射医学与公共卫生学院卫生毒理学教研室江苏省放射医学与防护重点实验室,江苏苏州215123
出 处:《环境与职业医学》2009年第2期148-151,共4页Journal of Environmental and Occupational Medicine
摘 要:[目的]观察手机频段(900MHz)微波辐射对小鼠头部表面温度、非空间学习记忆能力和对外界环境兴奋性的影响。[方法]采用900MHz、90μW/cm2微波辐照小鼠2h,于辐照前、辐照中不同时间点和辐照后20min测量小鼠头部表面温度。避暗反应和开放场实验中,将小鼠随机分为3组:对照组,一次微波辐射组(功率密度90μW/cm2、辐照1h),持续微波辐射组(功率密度90μW/cm2、1h/d、持续辐照10d);比较微波辐射不同时间后小鼠学习记忆能力和对外界环境兴奋性的不同。[结果]辐射组小鼠随着辐照时间的延长,头部表面温度逐渐升高;在辐照100min时达最高点,与辐照前相比升高(2.95±0.48)℃;此后温度有所下降,但仍明显高于对照组(P<0.01)。避暗实验中,一次微波辐射组与持续微波辐射组接受不同时间辐照后的潜伏期、错误次数差异均无统计学意义。开放场实验中,一次微波辐射组,辐照30min后较辐照前活动时间减少(P<0.05),停止辐照后30min的活动时间仍减少(P<0.05);持续微波辐射组,辐照6d后较辐照前小鼠总路程增加(P<0.05),平均速度增加(P<0.01),休息时间减少(P<0.05)。[结论]900MHz、90μW/cm2微波辐射对小鼠可能存在热效应;一次微波辐射和持续微波辐射,一定程度上影响了小鼠对外界环境的兴奋性,但对小鼠非空间学习记忆能力无明显影响。[ Objective ] To investigate the effects of 900 MHz microwave radiation on the head surface temperature, learning and memory abilities and the excitability upon environment in mice. [ Methods ] Kunming mice were exposed to 900MHz, 90μW/cm^2 microwave radiation. The head surface temperature of mice was measured at different time points of radiation using a infrared thermal imager. The learning and memory abilities before and after radiation were studied by means of step through test, and the excitability upon environment was studied with open field test. [ Results ] The head surface temperature of mice in exposure group increased with radiation time, and reached the highest point after 100 min radiation. In the step-through test, there was no apparent difference for the latency and error integral after radiation for one time or repeated times. In the open field test, for one time radiation group, the move time was significantly decreased after 30 min exposure (P 〈 0.05 ). For repeated radiation group, the total distance and the move time of mice increased ( P 〈 0.05 ), the mean speed increased ( P 〈 0.01 ) after 6 days radiaton compared with that of the same group before radiation. [ Conclusion ] 900 MHz, 90μW/cm^2 microwave radiation could have thermal effects in mice. One time or repeated microwave radiation may affect the excitability of mice to a certain extent. The non-space learning and memory abilities in mice were not markedly influenced.
分 类 号:R338[医药卫生—人体生理学]
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