多氯联苯的内分泌影响及机制  

A Review on the Endocrine Effect of Polychlorinated Biphenyls and Its Mechanisms

作　　者：王红梅[1] 段小丽[1] 王跃文[2] 全占军[1] 王菲菲[1] 

机构地区：[1]中国环境科学研究院,北京100012 [2]江苏工业学院环境安全工业学院,江苏常州213016

出　　处：《环境与职业医学》2009年第2期191-194,共4页Journal of Environmental and Occupational Medicine

基　　金：国家科技部中国科研院所社会公益研究专项(编号:HBGY200709022)

摘　　要：多氯联苯(PCBs)是一组氯代烃类化学物质,作为一种常见的环境污染物,其物理化学性质决定了它们能够持久地存在于环境中并具有生物蓄积性。它可以通过大气、土壤、动植物产品和食品等多种暴露途径进入人体并在体内富集,对人类健康产生不良影响。本文综述分析报道近年来有关PCBs影响内分泌系统的实验研究、人群暴露效应及相关机理的研究进展。Polychlorinated biphenyls （ PCBs ） are chlorinated organic chemicals belonging to a class of hydrocarbons. Being an environmental contaminant, their physical and chemical properties allow them to persist in the environment for a long time and to be bioaccumulative. PCBs could accumulate in organism and affect health by different exposure paths, such as air, soil, animal ＆ plant, and food. This paper summarizes the research progress of PCBs impacting on endocrine system, their exposure effect, as well as their mechanism.

关 键 词：多氯联苯 内分泌 作用机制 

分 类 号：R114[医药卫生—卫生毒理学]