银杏天宝预防冠脉搭桥术后再发心绞痛疗效观察  

Effects of the Extract of Ginkgo Biloba(EGB) on the Angina Pectoris after Coronary Artery Bypass Graft

作　　者：胡佳心[1] 林宇[1] 阮新民[1] 林冬群[1] 陈晓伟[1] 

机构地区：[1]广东省中医院二沙分院心胸外科,广东广州510105

出　　处：《辽宁中医杂志》2008年第12期1863-1865,共3页Liaoning Journal of Traditional Chinese Medicine

摘　　要：目的:探讨银杏天宝预防冠脉搭桥术后再发心绞痛的疗效。方法:60例冠脉搭桥病人,随机分成银杏天宝组(治疗组)和非银杏天宝组(对照组)各30例,对照组术后常规应用西药抗凝、扩冠和降压治疗,治疗组在对照组的基础上,加用银杏天宝共观察12个月。结果:术前平均每天心绞痛次数和持续时间两组间无显著差异,而术后1年则差别明显(P<0.05),且术后1年治疗组对减轻再发心绞痛的总有效率明显好于对照组(P=0.042)。术前心电图显示ST-T波的抬高或压低以及心律失常情况,两组无显著性差异,而术后1年则银杏天宝组明显好于对照组(P<0.05)。术后1年治疗组心功能改善明显好于对照组(P=0.008)。结论:银杏天宝对减轻冠脉搭桥术后再发心绞痛有比较好的疗效。Objective：To explore effects of the extract of ginkgo biloba（EGB） leave on recurrent angina pectoris after coronary artery bypass graft. Methods：60 cases patients with coronary artery disease who would be underwent surgery were divided randomly into the treatment group （30 cases）and the control group （30 cases）. The control group were treated with conventional method of isosorbide Dinitrate, aspirin, Betaloc and Norvasc, and the treatment group were treated with EGB 80mg P. O. three times a day, on the basis of the conventional method. Both groups of patients were treated for consecutive 12 months. The parameters of angina pectoris,electrocardiogram and ejective fraction were measured in preoperation and postoperative 12 months. Results：The times and period of angina pectoris ,ST- T variation and arrhythmia of ECG were much less in treatment group than in control group at postoperative 12 months, moreover, ejective fraction value were much higher in treatment group than in control group 12 months after coronary artery bypass. Conclusion：The EGB exerts significant effects on recurrent angina pectoris after coronary artery bypass.

关 键 词：银杏天宝 冠心病 冠脉搭桥术后 

分 类 号：R587.1[医药卫生—内分泌]