摘除小鼠颌下腺其附睾内精子数的变化  

NUMBER CHANGE OF EPIDIDYMIS SPERM IN MICE AFTER SIALOADENECTOMY

作　　者：唐向辉[1,2] 和协超 周曾娣[1,2] 黎曼侬 陈云鹤 

机构地区：[1]中国科学院昆明动物研究所 [2]云南省计划生育所

出　　处：《解剖学报》1998年第2期204-206,共3页Acta Anatomica Sinica

基　　金：国家计划生育委员会科研基金

摘　　要：为观察１４周龄雄性昆明种小白鼠施行颌小腺摘除后１～６周附睾内成熟精子数量的变化，取小鼠４８只，随机分成１２组，其中６组行颌下腺摘除手术，其余为对照。结果表明，颌下腺摘除后第４周开始，附睾内精子数量呈显著减少趋势，第５和第６周的精子数分别为０．５６±０．２６×１０７和０．５０±０．１３×１０７，与对照相比分别有显著差异（Ｐ＜０．０５）和非常显著差异（Ｐ＜０．０１）。摘除颌下腺手术后５周内小鼠的体重与对照相比无显著变化，但第６周的体重下降有明显的统计学差异（Ｐ＜０．０１）。Sialoadenectomy was employed to study the effects of the submaxillary glands on the sperm numbers of the epididymis in mice.48 male Kunming albino mice(14 week old) were randomly divided into 12 groups.The removal of the submaxillary glands was conducted among six groups(4 mice per group).The control that was age and weight matched six groups(4 mice each group) male mice had received sham operation.The epididymis sperms were counted each week after the operation.By 5 and 6 weeks after the sialoadenectomy, numbers of mature sperm in the epididymis were 0 56±0 26×10 7 and 0 50±0 13×10 7,respectively,and decreased 50 percent( P <0 01).The body weight in sialoadenectomized mice was also somewhat less than that of control.Results showed that the submaxillary glands might be related with spermatogenesis in mice.

关 键 词：颌下腺 附睾 精子数量 小鼠 

分 类 号：R321.1[医药卫生—人体解剖和组织胚胎学] R335.9[医药卫生—基础医学]