PTFV_1对左心室射血分数正常的原发性高血压患者的临床意义  

Clinical significance of PTFV1 for essential hypertension with normal left ventricular ejection fraction

作　　者：杨红玲[1] 黄新平[1] 孙琳[1] 刘帆[1] 杜波[1] 

机构地区：[1]大理学院附属昆明医院心内科,云南昆明650011

出　　处：《云南医药》2009年第2期144-146,共3页Medicine and Pharmacy of Yunnan

摘　　要：目的探讨PTFV1(V1异联P波终末电势)在左心室射血分数正常的原发性高血压患者中的临床意义。方法选择左室射血分数(LVEF)正常的原发性高血患者232例,通过描记12导联体表心电图,计算PTFV1值,以PTFV1<-0.03mm.s为阳性标准,将患者分为观察组(即PTFV1<-0.03mm.s)156例,对照组(即PTFV1≥-0.03mm.s)76例,对比2组间左房内径(LAD),左室舒张末期内径(LVEDD),室间隔厚度(IVST),左室后壁厚度(PWT)及左心室舒张早、晚期流速峰值比(E/A)的差异。结果观察组LAD,LVEDD,IVST,PWT值均较对照组升高,分别为(37.15±4.27)VS(27.66±2.10)mm,(48.42±6.80)VS(41.20±4.61)mm,(12.15±2.05)VS(10.06±1.11)mm,(11.70±2.11)VS(9.89±1.32)mm,均P<0.01;观察组E/A值较对照组降低0.68±0.12VS1.06±0.11mm,P<0.01。结论在左室射血分数正常的原发性高血压患者中,PTFV1<-0.03mm.s提示患者存在着左室舒张功能障碍,PTFV1对于高血压患者心功能状况的早期诊断有一定意义。Objective To study the clinical significance of PTFV1 changes in essential hypertension with normal left ventricular ejection fraction（LVEF）. Methods A total of 232 essential hypertension patients with normal LVEF were divided into 2 groups according to PTFV1 〈 -0.03mms as criteria.156 patients with PTFVt 〈 -0.03mm.s were observation group and another 76 patients with PTFV1〉-0.03mm.s were control group. The values of left atrium diameter （LAD）, left ventrieular end-diastolic diameter （LVEDD）, inter ventricular septum thickness （IVST）, left ventricular posterior wall thickness （PWT） and E/A were compared between both groups. Results Compared with control group, LAD, LVEDD, IVST and PWT values of observation group were increased, E/A values decreased, and the differences were significant （P 〈 0.01）. Conclusion For essential hypertension with normal LVEF, PTFV1 〈 -0.03mm.s would be suggested as left ventricle diastolic function disturbance.

关 键 词：PTFV1 原发性高血压病 左室射血分数 舒张功能 

分 类 号：R541.2[医药卫生—心血管疾病]