42例散发戊型肝炎临床与病原学观察  被引量:1

Clinical and serological analysis of scattered hepatitis E

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作  者:武菲菲[1] 王金花[1] 陈志娇[1] 王菊英[1] 希向红 

机构地区:[1]宁夏医学院附属医院传染科

出  处:《宁夏医学杂志》1998年第2期80-81,共2页Ningxia Medical Journal

摘  要:目的进一步观察戊型肝炎临床与病原学。方法对1004例住院的各型病毒性肝炎,用EIA法检测甲~戊五型病毒性肝炎血清标志。结果检出抗HEV阳性42例,检出率为4.18%。低于同期HBV和HAV感染,居HAV~HEV五型感染的第三位。并对42例HEV感染者进行了临床及病原学观察,显示以男性青壮年多见。HEV与HBV、HAV双重感染高于单纯HEV感染(P<0.05),其中以HBV与HEV双重感染最多见,占HEV感染的71.42%。乙肝肝硬变重叠HEV感染易出现病情加重,恢复迁延,预后欠佳。结论HAV与HEV双重感染比单纯HEV感染发病年龄下移(P<0.05),但病情无加重。戊型重型肝炎发病率较高。HEV多重感染,临床恢复迁延。bjective In order to observe clinic and serological of Hepitatis E Virus. Methods Serum Marker of the patients with of Hipitatis Virus in patient was tested by the method of EIA.Anti-HEV was tested in 1004 patients with varied viral hepatitis.There were 42 cases whose Anti-HEV were positive. Results The positive rate was 4.18% which was lower than that of HBV and HAV within same peariod.HEV infection was more often in young and middle aged people.HEV/HBV and HEV/HAV superinfection were more often as compared with HEV infection alone(P<0.01).HEV/HBV superinfection was the greater part of the 42 cases (71.42%).HEV superinfection in hepatitis B cirrhosis would result in the worsening of the hepatopathy,prolongation of the course of disease and doubtful prognosis. Conclusion The age of HEV/HAV superinfection was decreased when compared with that of HEV infection alone (P<0.05).The attack rate of fulminant E hepatitis was high.HEV multiinfection can prolong the course of disease.

关 键 词:戊型肝炎 散发性 病原学 

分 类 号:R512.630.2[医药卫生—内科学]

 

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