神经组织工程修复脊髓损伤中的种子细胞  

Seed cells in neuro-tissue engineering on repairing spinal cord injury

作　　者：曾晗冰[1] 李士[1] 李万里[2] 徐华梓[1] 

机构地区：[1]温州医学院附属第二医院骨科,浙江温州325027 [2]浙江大学医学院附属第二医院骨科,浙江杭州310009

出　　处：《中国矫形外科杂志》2009年第8期600-603,共4页Orthopedic Journal of China

基　　金：温州市科技局对外合作项目(编号:H20080031);浙江省自然科学基金项目(编号:Y2080507)

摘　　要：脊髓损伤后局部产生的各种抑制因子以及神经断端之间的瘢痕都是脊髓损伤难以修复的重要原因。通过细胞移植不仅可以补充局部损失的细胞,而且可以促进损伤脊髓功能的恢复。本文对脊髓损伤修复中的各种常见种子细胞进行了综述,并对各种细胞的优缺点进行了讨论。最后根据目前的研究现状,对细胞移植治疗脊髓损伤的研究趋势进行了展望。The inhibitory environment and loss of axonal connections after spinal cord injury pose many obstacles to regenerating the lost tissue. Cellular therapy provides a means of restoring the cells lost to the injury and could potentially promote functional recovery after such injuries. This review presents a summary of the various types of cellular therapy used to treat spinal cord injury. A wide range of cell types have been investigated for such uses and the advantages and disadvantages of each cell type are discussed along with the research studying each cell type. Based on the current research, suggestions are given for future investigation of cellular therapies for spinal cord regeneration.

关 键 词：脊髓损伤 组织工程 神经组织 种子细胞 修复 

分 类 号：R651.2[医药卫生—外科学]