妊娠高血压综合征患者血清C_3、C_4及CRP水平变化及意义  

Changes and significance of serum C_3,C_4 and CRP levels in patients with pregnancy induced hypertension

作　　者：张俊[1,2] 李荣国[2] 毛海婷[1,3] 

机构地区：[1]山东省医学科学院,山东济南250062 [2]济南市妇幼保健院 [3]山东大学齐鲁医院

出　　处：《山东医药》2009年第15期20-21,共2页Shandong Medical Journal

摘　　要：目的探讨C3、C4、CRP在妊娠高血压综合征(PIH)发病中的作用。方法采用免疫比浊法检测30例PIH患者(PIH组)、20例正常晚期妊娠妇女(晚妊组)、20例正常育龄非孕妇女(非孕组)外周血中C3、C4、CRP水平。结果PIH组C3、C4明显低于晚妊组及非孕组,P均<0.05。结论补体及炎症参与了PIH的发生、发展;动态监测血清C3、C4、CRP有助于PIH的早期诊断。Objective To investigate the roles of C3 ,C4 and CRP in the pathogenesis of pregnancy induced hypertension （PIH）. Methods The serum levels of C3 , C4 and CRP of 30 patients with pregnancy induced hypertension （ PIH group） ,20 normal late pregnant women（ NLP group） and 20 normal non-pregnant women（ NNP group） were detected by immunoturbidimetry. Results Compared with the NLP and NNP group, serum levets of C3 ,C4 in the PIH group decreasedand CRP increased significantly. Conclusions Complements and inflammation involved in morbidity and progression of PIH; Dynamic monitoring of serum level of C3 ,C4 and CRP will be helpful to early diagnosis of PIH.

关 键 词：妊娠高血压综合征 补体 C反应蛋白 

分 类 号：R714.26[医药卫生—妇产科学]