探讨高血压合并冠心病脉搏波速度变化特点  

A study on the characteristics of baPWV in patients with essential hypertension associated with coronary artery disease

作　　者：邓昌明[1] 黄晶[1] 刘地川[1] 杨刚[1] 罗开良[1] 

机构地区：[1]重庆医科大学附属第二医院心血管内科,重庆400010

出　　处：《重庆医科大学学报》2009年第4期494-495,共2页Journal of Chongqing Medical University

基　　金：重庆市卫生局科研基金资助项目(渝卫科教2005-31);重庆市自然科学基金资助(CSTC2006BB5280)。

摘　　要：目的:探讨原发性高血压以及高血压合并冠心病患者脉搏波速度变化规律。方法:选取2007年11月～2008年10月心血管内科原发性高血压患者28例;高血压合并冠心病患者25例,冠心病患者均接受冠状动脉造影,至少有一支冠状动脉狭窄≥50%;同时选取健康者26例为对照组。所有入选者均为窦性心律,均接受脉搏波速度检测。结果:原发性高血压患者与健康对照组比较,高血压患者baPWV明显升高(P<0.01),而高血压合并冠心病者baPWV比单纯高血压患者升高更为明显(P<0.01)。结论:原发性高血压患者血管弹性减低,僵硬度增加;而高血压合并冠心病者血管损害更加明显,血管硬化加重,弹性显著下降。Objective： To investigate the characteristics of brachial ankle pulse wave velocity （baPWV） in patients with essential hypertension, and that in patients with essential hypertension associated with coronary artery disease. Methods ： The baPWV of 28 patients with essential hypertension was measured, the baPWV of 26 patients with essential hypertension associated with coronary artery disease confirmed by coronary angiography was also measured, and the baPWV of 25 control group＇s patients was measured. Results： baPWV was significantly higher in patients with essential hypertension than that in contral group, and baPWV is much higher in patients with essential hypertension associated with coronary artery disease than that in patients with essential hypertension. Conclusions：The results suggest that vascular lesion is exsist in patients with essential hypertension,and the vascular stiffness in patients with essential htpertension associated with coronary artery disease is increased than that in patients with essential hypertension.

关 键 词：臂踝脉搏波速度 高血压 冠心病 冠状动脉造影 

分 类 号：R544.1[医药卫生—心血管疾病]