尿微量白蛋白与老年糖尿病并发脑梗死的关系  

Relationship between urine microalbumin and cerebral infarction in elderly diabetic patients

作　　者：林爱清[1] 李明龙[1] 李娟[1] 井月秋[1] 

机构地区：[1]山东大学附属省立医院保健内分泌科,济南250021

出　　处：《老年医学与保健》2009年第2期92-93,111,共3页Geriatrics & Health Care

摘　　要：目的观察老年糖尿病患者尿微量白蛋白排泄率（UAER）与脑梗死的关系，并对其他相关危险因素进行分析。方法对收治的105例老年糖尿病患者，按是否合并脑梗死分两组，测定各组患者的空腹血糖（FBG）、糖化血红蛋白（HbAlC）、血脂、UAER等指标并进行相关影响因素的Logistic回归分析。结果糖尿病并发脑梗死组UAER、FBG水平均高于糖尿病非脑梗死组（P〈0．01），多因素回归分析显示老年糖尿病并发脑梗死与UAER（r=0．533P〈0．01）、FBG（r=0．457，P〈0．05）均呈正相关。结论尿微量白蛋白和空腹血糖是老年糖尿病患者并发脑梗死的两个独立危险因素，积极控制患者空腹血糖和降低UAER，可减少老年糖尿病患者并发脑梗死。Objective To observe the relationship between urinary albumin excretory rate （UAER） and cerebral infraction （CI） in elderly patients with diabetes mellitus （DM）, and analyze other related risk factors. Methods According to the presence or absence of complicated CI, 105 elderly diabetic patients were divided into two groups： 40 diabetic patients without CI （group DM） and 65 diabetic patients with CI （group DM＋CI）. Fasting blood glucose （FBG）, HbAlC, serum lipids and UAER were detected. Risk factors of complicating DM with CI were analyzed using multivariate logistic regression. Results Both UAER and FBG in group DM＋CI were significantly higher than those in group DM （both P〈0.01）. Logistic regression analysis showed that UAER （r=0.533 P〈0.01） and FBG （r=0.457, P〈0.05） were associated positively with CI in elderly diabetic patients. Conclusions These data suggest that UAER and FBG are two independent risk factors of complicating DM with CI in elderly patients. Good glucose control and decreasing UAER could reduce the morbidity rate of CI in old diabetic patients.

关 键 词：白蛋白尿 糖尿病 脑梗塞 血糖 

分 类 号：R587[医药卫生—内分泌]