佛山地区人群血清丙型肝炎病毒抗体的阳性率及检测意义  

Detection of the positive rate of serum hepatitis C virus antibody in Foshan region and its clinical significance

作　　者：关幼华[1] 肖志超[1] 梁玉珊 

机构地区：[1]广东省佛山市南海区人民医院检验科,528200

出　　处：《检验医学与临床》2009年第8期561-562,共2页Laboratory Medicine and Clinic

摘　　要：目的了解佛山地区人群血清丙型肝炎病毒抗体(抗-HCV)的阳性率、丙型肝炎病毒(HCV)主要传播方式以及在普通人群中展开抗-HCV检测的意义。方法用酶联免疫吸附试验法检测2001～2007年佛山地区人群血清抗-HCV,统计每年的阳性率,观察HCV感染趋势。通过病史调查观察传播方式的变化。结果2001～2007年抗-HCV阳性率依次为0.42%、0.44%、0.45%、0.45%、0.46%、0.47%、0.48%,呈轻微上升趋势,输血感染HCV占主要比例,但总体呈下降趋势,而静脉吸毒引起的HCV感染占第2位,且呈上升趋势。结论2001～2007年佛山地区HCV感染呈每年轻微上升趋势,情况不可轻视,输血及静脉吸毒是主要传播方式,在普通人群中展开抗-HCV检测可有效地掌握人群中HCV感染情况,对丙型肝炎患者的早期发现及阻止HCV在人群中传播有重要意义。Objective To investigate the positive rate of serum anti-HCV and the main mode of transmission of HCV in Foshan region,and evaluate the clinical significance of anti-HCV detection in common people. Methods Enzyme linked immunosorbent assay （ELISA） was applied to detecting serum anti-HCV in people in Foshan region from 2001 to 2007; the annual positive rate was recorded,and the HCV infection tendency was observed. The variability of infection way was investigated by investigating the case history. Results The positive rates of anti-HCV from 2001 to 2007 were 0. 42%,0. 44%,0. 45%0. 45%,0. 46%,0. 47% and 0. 48% respectively, displaying a slightly rising trend. HCV infection due to blood transfusion was dominant,displaying a declining tendency; followed by that due to venous narcotic taking, displaying a slightly rising trend. Conclusion There is a slightly ascendent tendency in HCV infection in Foshan region from 2001 to 2007 and the situation shouldn＇t be despised. Blood transfu- sion and venous drug taking are the main infection ways. It plays an important role to availably grasp the situation of HCV infection by detecting serum anti-HCV in common people in early diagnosis of hepatitis C and timely prevention of HCV transmission in crowd.

关 键 词：丙型肝炎病毒 抗体 酶联免疫吸附试验 

分 类 号：R446.1[医药卫生—诊断学] R512.63[医药卫生—临床医学]