Synthesis of fused pyran and arylbis(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)methane in ionic liquid  

作　　者：Xue Sen Fan Ying Ying Qu Xin Ying Zhang Xia Wang Jian Ji Wang 

机构地区：[1]School of Chemistry and Environmental Sciences, Henan Key Laboratory for Environmental Pollution Control, Henan Normal University, Xinxiang 453007, China

出　　处：《Chinese Chemical Letters》2009年第4期387-390,共4页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China(No.20772025);the Program for Science & Technology Innovation Talents in Universities of Henan Province(No.2008HASTIT006);the Natural Science Foundation of Department of Education of Henan Province(No.2008A150013).

摘　　要：Promoted and mediated by an ionic liquid-[bmim][BF4], fused pyrans or arylbis（4-hydroxy-6-methyl-2-oxo-2H-pyran-3- yl）methanes were efficiently and selectively prepared from the reaction of aldehyde and 4-hydroxy-6-methyl-2-oxo-pyran with or without acetic anhydride. By using these novel procedures, pyrimidine nucleoside-fused pyran and arylbis（pyranon-3-yl）methane hybrids with potential biological activities were constructed.Promoted and mediated by an ionic liquid-[bmim][BF4], fused pyrans or arylbis（4-hydroxy-6-methyl-2-oxo-2H-pyran-3- yl）methanes were efficiently and selectively prepared from the reaction of aldehyde and 4-hydroxy-6-methyl-2-oxo-pyran with or without acetic anhydride. By using these novel procedures, pyrimidine nucleoside-fused pyran and arylbis（pyranon-3-yl）methane hybrids with potential biological activities were constructed.

关 键 词：Ionic liquid Fused pyran Arylbis（4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl）methane Pyrimidine nucleoside Green synthesis 

分 类 号：O646.1[理学—物理化学] TQ655[理学—化学]