SELDI技术及其在肺相关疾病研究中的应用  

SELDI Technique and Its Application in Lung-related Diseases Research

作　　者：邓青南[1] 周建龙[1] 张萍[1] 

机构地区：[1]广州军区广州总医院,广州510010

出　　处：《医疗卫生装备》2009年第4期33-36,共4页Chinese Medical Equipment Journal

基　　金：广东省科技计划项目(2008B030301197)

摘　　要：概述了近年来出现的SELDI蛋白芯片技术在肺相关疾病等方面良好的应用现状,为该技术在肺相关疾病中的应用提供参考。SELDI蛋白芯片技术是一种自动快捷、灵敏特异、高通量的蛋白组学研究方法,运用该技术可大大提高肺相关疾病诊断的准确性,解决了目前肺相关疾病诊断较难、较慢的情况,对其优势、劣势进行了分析。指出SELDI蛋白芯片可提高肺相关疾病诊断的特异性和阳性率等,具有良好的应用前景。The development of protein chip technique in clinical diagnosis of lung-related diseases are reviewed to provide the references for the application of technique in other diseases. The SELDI technique is a high throughput research method in proteomics with superiorities of automation, rapidness, sensitivity and specificity. It has widely potential application in clinical diagnosis of lung-related diseases. Its principle, classification, apphcation, analysis and advantage are introduced. The protein chip technique improves positive ratio and specificity of lung-related diseases diagnosis.

关 键 词：蛋白质芯片 表面增强激光解吸/电离 肺相关疾病 

分 类 号：R346[医药卫生—基础医学] R563