应用类同轴技术开展肾脏相位成像的实验研究  

Experimental Investigation of Kidney Phase Contrast Imaging with In-line Holography Technology

作　　者：彭屹峰[1,2] 陈绍亮[3] 肖体乔[2] 徐洪杰[2] 陈岳声[1] 汤光宇[1] 

机构地区：[1]同济大学附属第十人民医院放射科,上海200072 [2]中国科学院上海应用物理研究所同步辐射实验部 [3]复旦大学附属中山医院核医学科

出　　处：《中国医学计算机成像杂志》2009年第2期177-179,共3页Chinese Computed Medical Imaging

基　　金：国家自然科学基金(No.30471652)~~

摘　　要：目的:应用同步辐射光源的相干性,进行肾脏组织的类同轴成像研究,旨在评价相位衬度成像技术在软组织成像方面的意义。方法:在北京同步辐射装置形貌站4W1A束线上,取经过4%甲醛溶液固定后的人体肾脏组织样品,置于类同轴光路的样品架上进行成像,以空间分辨率和组织衬度作为评价标准。结果:在样品与成像板距离Z为150mm获得的肾脏成像,具有较高的组织衬度,包括肾小囊在内的结构均能较好显示,通过显微放大法获得的空间分辨率达到30μm。结论:类同轴技术能较好显示肾脏的微细解剖结构,对于以轻元素为主的脏器成像有较好的应用价值。Purpose： To evaluate the latent value in soft tissue imaging with phase contrast technology. To carry out kidney study which was performed with In - line holography imaging technology base on the coherence character of Synchrotron radiation（SR） .Methods： The experiments were performed in the 4W1A of the BSRF （Beijing synchrotron radiation facility in china）, the samples were soaked in 4% formalin solution, and then were imaged on the shelf and in the ＂in - line＂ holography imaging setup. The spatial resolution and tissue contrast were served as evaluate elements. Results： When the distance was 150mm between the samples and imaging plate, good contrast and high resolution were obtained in the ＂in - line＂ phase contrast imaging, as such renal capsule was revealed well, and the resolution reached 30 micron. Conclusion： The minuteness structure of kidney is well presented with in - line holography imaging which is good for the applying of main light element organ imaging.

关 键 词：同步辐射 相位衬度 类同轴成像技术 肾脏 

分 类 号：R816.7[医药卫生—放射医学]