高山红景天首次分离的化合物(Ⅰ)  

Compounds Isolated Firstly from Rhodiola Sachalinensis A. Bor

作　　者：侯奋争[1] 姚桂彬[1] 徐伟[1] 李玉山[1] 

机构地区：[1]沈阳药科大学生药学教研室,辽宁沈阳110016

出　　处：《中国现代中药》2009年第4期18-20,共3页Modern Chinese Medicine

摘　　要：目的:对高山红景天药材进行化学成分研究。方法:高山红景天根及根茎的乙醇提取物,经正相硅胶柱、ODS柱、SephadexLH-20凝胶柱色谱以及半微量制备型HPLC色谱分离、纯化。结果:分离得到7个单体化合物,经谱学数据及理化性质鉴定为熊果苷(arbutin,1)、表百脉根苷(epilotaustralin,2)、垂盆草苷(sarmentosin,3)、红景天苷(salidroside,4)、苄基-β-D-葡萄糖苷(benzyl-β-D-glucopyranoside,5)、络塞维(rosavin,6)和百脉根苷(lotau-stralin,7)。结论:化合物1～3为首次从高山红景天中分离得到。Objective： To investigate chemical constituents of Rhodiola sachalinensis A. Bor. Methods： The rhizoma and the root of R. sachalinensis A. Bor were extracted with ethanol, and the ethanol extract was separated and purified by silica gel , ODS and Sephadex LH-20 column, followed by reversed-phase semimicropreparation HPLC chromatography. The structures of these compounds were elucidated on the basis of spectral analysis. Results： Seven compounds were isolated and identified as ： arbutin （ 1 ） , epilotaustralin （ 2 ） , sarmentosin （ 3 ） , salidroside （4） , benzyl-β-D-glucopyranoside （5）, rosavin （6）, and lotaustralin （7） . Conclusion： The compounds 1 -3 were isolated from R. sachalinensis A. Bor for the first time.

关 键 词：高山红景天 熊果苷 百脉根苷 垂盆草苷 

分 类 号：R284.1[医药卫生—中药学] R282.71[医药卫生—中医学]