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出 处:《世界中西医结合杂志》2009年第4期266-267,270,共3页World Journal of Integrated Traditional and Western Medicine
基 金:广东省中医药管理局基金资助项目(No.2060056)
摘 要:目的观察中西医结合方法治疗慢性乙型病毒性肝炎的临床疗效。方法将60例慢性乙型病毒性肝炎随机分为对照组与治疗组,每组各30例。对照组患者单纯应用拉米呋啶片治疗,治疗组在对照组治疗基础上加用乙肝方。观察两组患者的临床疗效及ALT复常、HBsAg阴转、HBeAg血清转换、HBV-DNA情况。结果对照组总有效率为63.33%,治疗组为86.67%,两组比较有显著性差异(P<0.05)。治疗组治疗后ALT复常、HBeAg血清转换、HBV-DNA转阴情况均优于对照组(P<0.05)。结论中西医结合治疗慢性乙型病毒性肝炎,疗效显著,可缩短疗程,降低停药后的复阳率,值得进一步推广应用。Objective To observe the clinical therapeutic effect on chronic viral hepatitis B treated with integrative Chinese and western Medicine.Methods 60 cases of chronic viral hepatitis B were randomized into control group and treatment group,30 cases in each one.In control group,lamivudine tablet was provided in treatment.In treatment group,on the basis of the treatment as control group,Yigan Fang(formula for hepatitis B)was supplemented.It was to observe clinical efficacy,ALT recovery,HBsAg negative conversion,HBeAg seroconversion and HBV - DNA in two groups. Results The total ettective rate was 63.53% in control group and was 86.67% in treatment group, indicating significant difference in comparison( P 〈 0.05 ). ALT recovery, HBeAg seroconversion and HBV - DNA negative conversion after treatment in treatment group were all superior to those in control group (P 〈 0.05 ). Conclusion Integrative Chinese and western medicine presents significant efficacy on chronic viral hepatitis B. It shortens the duration of treatment and reduces the recurrence rate after discontinuity of medication. Hence ,this therapy deserves further promotion.
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