探讨RIA测定甲状腺激素水平的影响因素  

The Influence Factors on the Determination of Thyroid Hormone Level by RIA

作　　者：王华新[1] 李云凤[1] 何卫社[2] 李延伟 王红[4] 张海涛[1] 于水江[1] 吴英杰[1] 蔡会欣[5] 孙欣[2] 

机构地区：[1]河北省黄骅开发区博爱医院,河北黄骅061100 [2]廊坊市人民医院,河北廊坊065000 [3]张家口市血站,河北张家口075000 [4]保定市第一中医院,河北保定071000 [5]保定市第一中心医院,河北保定071000

出　　处：《标记免疫分析与临床》2009年第2期96-98,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：探讨RIA测定甲状腺激素水平的影响因素(运动、饮食、生物节律、药物)对测定结果的影响。T3、T4、FT3、FT4为RIA法,TSH为IRMA法。结果表明,运动、饮食测定结果与对照无显著性差异;轻度脂血对测定结果无影响,重度脂血有影响趋势;TSH昼夜间变化明显,T3、T4、FT3、FT4无昼夜变化;甲状腺素片对T3、T4、FT3、FT4测定结果影响明显,他巴唑对测定结果无影响。RIA测定甲状腺激素应试者状态至关重要,是保证检验结果准确性的先决条件,要高度重视。To explore the influence factors such as movement, diet and biothythm of subjects on the determination of thyroid hormone level by RIA, the serum T3, T4, FT3 and FT4 levels were determined by RIA and TSH level measured by IRMA. The results showed that there were no significantly difference of thyroid hormone level between the movement, diet and light lipemia groups and controls, but the serious lipemia was impact tendency on the measurement. There were obviously changes on the TSH levels between day and night, while no impacts on T3 , T4, FT3 and FT4 levels. The thyroxine sodium tablets had obviously impact on the determination of T3 , T4, FT3 and FT4 levels, while no impact with thiamazole tablets. The status of subjects on the determination of thyroid hormone level by RIA is very important to guarantee the accuracy of measurement results.

关 键 词：放射免疫分析技术 甲状腺激素 生物节律 药物 影响因素 

分 类 号：R817.4[医药卫生—影像医学与核医学]